Microfluidic synthesis of monodisperse polymer microparticles with tunable concave/concave shapes
نویسندگان
چکیده
منابع مشابه
Synthesis of monodisperse microparticles from non-Newtonian polymer solutions with microfluidic devices.
Microfluidic devices can form emulsions that are highly uniform in size;[1–3] they can also form compound emulsions, in which each supradroplet contains exactly the same number of internal droplets, packed in exactly the same configuration.[4–6] Because the drops can be formed with a highly controlled structure and uniformity, they are useful as templates to synthesize monodisperse particles. I...
متن کاملMicrofluidic synthesis of monodisperse porous microspheres with size-tunable pores
We use a perfluorinated-dendrimer–dye complex that stabilizes microbubbles as a novel pore-forming agent. We use microfluidics to produce monodisperse emulsions containing a polymer matrix material, a model active, and the perfluorinated complex; upon drying, the emulsions form porous microspheres. This porosity causes the encapsulated model active to be released faster than from non-porous mic...
متن کاملPreparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery.
Degradable microparticles have broad utility as vehicles for drug delivery and form the basis of several therapies approved by the US Food and Drug Administration. Conventional emulsion-based methods of manufacturing produce particles with a wide range of diameters (and thus kinetics of release) in each batch. This paper describes the fabrication of monodisperse, drug-loaded microparticles from...
متن کاملMicrofluidic emulsification and sorting assisted preparation of monodisperse chitosan microparticles.
A microfluidic device for generating monodisperse chitosan microparticles and separating the desired particle from smaller particles created as a byproduct of this process was described. The purpose of this study is to separate the satellite droplets from their parent droplets to enhance the size uniformity of the desired microparticles. A double T-junction design was first employed to control ...
متن کاملTunable Morphology of Monodisperse Polymer Particles with Microfluidics
In this work, we propose a novel method to fabricate polymer particles with controlled morphology in microchannel by solidification of polymer solutions and study the transition in the shape of these particles from spheres, to cups, and to donuts. The non-spherical geometries are achieved through nonuniform diffusion of the solvent, leading to non-uniform solidification. By adjusting the flow r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hosokawa Powder Technology Foundation ANNUAL REPORT
سال: 2009
ISSN: 2189-4663
DOI: 10.14356/hptf.07116